Padres vs Nationals Predictions, Best Bets, and Picks

The San Diego Padres take on the Washington Nationals in tonight’s game at Nationals Park. This post delivers WAGERBIRD’s data-smart MLB prediction, betting insight, and sharp picks before the 6:45 PM ET first pitch.

Game Prediction

San Diego Padres

San Diego Padres

SD

VS
Jul 18
Starts at
6:45 pm
Nationals Park, Washington, DC
Washington Nationals

Washington Nationals

WSH

Jul 18
Starts at
6:45 pm
Nationals Park, Washington, DC

Pre-game wagerbirds

Full game
First Five Innings SD Team Total: U 2.5
wagerbird logo
61
wagerbird logo
Full Game Game Total
Confidence Rating:
wagerbird logo
lock icon
Full Game Run Line
Confidence Rating:
wagerbird logo
lock icon
Confidence Rating:
wagerbird logo
lock icon
Confidence Rating:
wagerbird logo
lock icon
Confidence Rating:
wagerbird logo
lock icon
Confidence Rating:
wagerbird logo
lock icon
Confidence Rating:
wagerbird logo
lock icon
wagerbird logo
This is just a few preview picks.
The rest are waiting in the terminal.
GET ACCESS

Betting Overview

Teams: San Diego Padres @ Washington Nationals
Date/Time: Friday, July 18, 2025 · 6:45 PM ET
Venue: Nationals Park, Washington, DC

Betting Odds

  • Moneyline: Padres around −168, Nationals approx. +150
  • Run Line: Padres −1.5, Nationals +1.5
  • Total (O/U): 8.5 runs

Preview of Padres vs Nationals Prediction

  • Probable Starters:
    • Padres: Dylan Cease — recently struck out 224 batters, 4.88 ERA over 103.1 IP
    • Nationals: MacKenzie Gore — All-Star, 3.96 ERA, 535 Ks on the season
  • Team Form & Trends:
    • Padres are 29–20 as ML favorites (~59% win rate)
    • Recent head-to-head: Padres won June and August 2024 matchups, Nationals won May 2025
  • Injury Updates:
    • Padres: C.J. Abrams scratched, SP Joe Musgrove out for season, Sean Reynolds tabbed to start
    • Nationals: No major changes; Gore remains healthy

This clash features two strong arms. Cease brings strikeout upside but inconsistency; Gore boasts elite K numbers but the Nats' lineup lacks depth. Expect a pitcher’s duel with modest offense, leaning slightly toward San Diego’s stronger batting.

Padres vs Nationals Predictions

Here are the WAGERBIRD Terminal picks for this matchup, based on algorithmic modeling and confidence scoring:

Free Pick

  • First Five Innings SD Team Total: U 2.5 (Confidence: 61)


Gated Picks (Terminal Access Required)

  • Full Game Game Total (Confidence: 68)
  • Full Game Run Line (Confidence: 64)

**Unlock the full Terminal MLB pick set and confidence breakdown in the WAGERBIRD Terminal.

FAQs

What chance do the Padres have of beating the Nationals?

WAGERBIRD's model gives San Diego ~60% win probability against Washington with current pitching and lineup trends.

How have the Padres fared as favorites recently?

They’ve gone 29–20 as moneyline favorites this season (~59% win rate) and 11–6 when listed at −168 or shorter (~65%).

Who is favored in tonight’s game?

The Padres are the clear favorites, backed by stronger recent performance and deeper batting.

Explore More Predictions Like Padres vs Nationals

Sign up for newsletter to unlock more insights

Want more picks like this?

Get access to the full board—confidence-ranked picks across every major sport, updated in real time.

wagerbird lineswagerbird lines