Padres vs Cardinals Predictions, Best Bets, and Picks
San Diego Padres head to Busch Stadium to tackle the St. Louis Cardinals tonight—this preview offers up-to-date odds, player insights, and WAGERBIRD's best MLB picks including a free top play.
Game Prediction
SD
STL
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Betting Overview
Teams: San Diego @ St. Louis
Date & Time: Thursday, July 24 at 7:45 p.m. ET
Venue: Busch Stadium, St. Louis, MO
Betting Odds
- Moneyline: Cardinals −153, Padres +128
- Run Line: Cardinals −1.5 (+140)
- Total: 8 runs (Over −117 / Under −104)
Preview of Padres vs Cardinals Prediction
St. Louis enters at 53% implied win probability, riding strong form with a 3–2 record in moneyline-heavy games ${turn0search2}, while the injury-shaken club recently DFA’d reliever Erick Fedde and brought up Andre Granillo (1.35 ERA in MLB). San Diego counters with MLB power duo Manny Machado (.285, 18 HR, 61 RBI) and Fernando Tatis Jr.—though their ace Joe Musgrove is out (Tommy John), pitching depth is thin. Models forecast a tight 5–4 St. Louis win and push toward Over (8 runs).
Padres vs Cardinals Predictions
Here are the WAGERBIRD Terminal picks for this matchup, based on algorithmic modeling and confidence scoring.
Free Pick
Full Game Money Line: STL — Confidence: 55
Gated Picks (Terminal Access Required)
- Full Game Game Total – Confidence: 58
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FAQs
How likely are the Padres to upset the Cardinals?
San Diego carries an implied ~47% moneyline win probability versus the Cardinals' 53%.
Who has the recent head-to-head edge?
St. Louis took the 2024 series 4–3, though the 2025 matchups are still open.
Who is favored tonight?
St. Louis leads across all lines—ML (−153), run line (−1.5), and total at 8—cementing their favorite status.
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