Giants vs Pirates Predictions, Best Bets, and Picks

San Francisco Giants take on the Pittsburgh Pirates tonight at PNC Park. This article covers lineups, odds, injury updates, and WAGERBIRD’s free pick ahead of first pitch at 6:40 PM ET.

Game Prediction

San Francisco Giants

San Francisco Giants

SF

VS
Aug 5
Starts at
6:40 pm
Citizens Bank Park, Philadelphia, PA
Pittsburgh Pirates

Pittsburgh Pirates

PIT

Aug 5
Starts at
6:40 pm
Citizens Bank Park, Philadelphia, PA

Pre-game wagerbirds

Full game
First Five Innings Game Total: U 4
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70
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First Five Innings SF Team Total
Confidence Rating:
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77
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Full Game SF Team Total
Confidence Rating:
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78
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Full Game Game Total
Confidence Rating:
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57
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Full Game Run Line
Confidence Rating:
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77
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Confidence Rating:
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Confidence Rating:
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Confidence Rating:
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Betting Overview

  • Teams: Pittsburgh Pirates vs San Francisco Giants
  • Date / Time: Tuesday, August 5, 2025 – 6:40 PM ET
  • Venue: PNC Park, Pittsburgh, PA

Betting Odds

  • Moneyline: Giants ≈ −138; Pirates ≈ +115
  • Run Line: Giants −1.5 at about +125; Pirates +1.5 at about −152
  • Total Runs: Over/Under set at 7.5 runs

Preview of Giants vs Pirates Prediction

San Francisco (56‑57) visits Pittsburgh (49‑64) as a slight road favorite. The Giants are struggling away (28‑31) but have been more effective when avoiding surrendering home runs. Meanwhile, Pittsburgh boasts a solid home record (32‑25) and has won four of the first five meetings in the series.

Probable pitchers: Logan Webb (Giants, 9‑8, 3.31 ERA) vs Mike Burrows (Pirates, 1‑3, 3.88 ERA, 1.24 WHIP). Pittsburgh also enters on a three‑game home win streak with good recent form.

Injury fronts: Giants are thin in pitching (Roupp, Miller on IL) and will rely on Justin Verlander for bullpen help. Pittsburgh continues to be shorthanded across both rosters. Meanwhile, San Francisco recently promoted Jerar Encarnacion, boosting offensive depth.

Giants vs Pirates Predictions

Here are the WAGERBIRD Terminal picks for this matchup, based on algorithmic modeling and confidence scoring.

Free Pick

  • First Five Innings Game Total: U 4 - Confidence: 70

Gated Picks (Terminal Access Required)

  • First Five Innings SF Team Total – Confidence: 77
  • Full Game SF Team Total – Confidence: 78
  • Full Game Game Total – Confidence: 57
  • Full Game Run Line - Confidence: 77

**Unlock full modeling insights and additional MLB picks in the WAGERBIRD Terminal.

FAQs

What chance does the Giants have of beating the Pirates?

Predictive models estimate roughly a 56–58% win probability for San Francisco.

How many times has the Giants beaten the Pirates this season?

Pittsburgh currently leads the season series 4‑0 through Game 1 of this matchup.

Who is favored to win Giants vs Pirates?

The Giants are favored by bookmakers with a moneyline around −138, implying roughly a 58% implied probability of victory.

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